The anti-vaxxer movement has, perhaps unsurprisingly, opposed Covid vaccines from the start, spreading baseless conspiracy theories both online and on the street at lockdown protests.
But even outside of these circles, the speed with which the vaccine has been developed – far faster than our usual understanding of how long it takes to reach such a development – has left many with questions about its safety.
Appearing on BBC Question Time, Professor Robin Shattock, an immunologist based at Imperial College London, sought to explain why we should be confident about vaccines.
He said: “I think we need to remember that vaccines, next to clean water, have been the single most effective public health implementation globally.
“They’ve saved more lives than any other medicines. People are concerned about this vaccine because they perceive that it’s been done too quickly, and actually we’ve done a disservice by saying ‘it takes ten years to make a vaccine’.
“Technology is changing very very quickly, and what has happened is the same number of participants have been exposed to this particular vaccine, 43,000 participants.”
Among the fears shared by those sceptical of a Covid-19 vaccine is the possibility of side effects that may not have had time to materialise as the trials have progressed.
But Shattock explained: “When you’re looking at side effects, most side effects occur very quickly. Within a week or so of have having a vaccine we would see any severe side effect at this stage.
“No regulatory authority, whether it’s the UK Medicines Regulatory Authority, or the European Regulatory Authority or the FDA will let anything go through that doesn’t have a totally squeaky clean safety record.
“One thing that I think people completely forget is that a vaccine stimulates your immune system, it tricks it to see if it’s seen the virus, so you’re getting an aspect of the infection that’s so much minor than the real virus.
“So when you think about the risk-benefit, the risk of having a severe outcome from Covid-19 far outweighs any theoretical risk of a vaccine, and the problem is that vaccines are so successful that diseases go away and all you see are the side effects.”
Amid months of pandemic disinformation, Shattock earned praise after a clip of his argument was posted on Twitter, with social media users complementing his “brilliant”, “clear” explanation.
The question isn't who is going to let me; it's who is going to stop me.